They're the new boulevards of death: major streets in every borough where pedestrians are mowed down again and again - and it's time the city tried to help, advocates charged yesterday.

More than half of all pedestrian fatalities and injuries occur at 10% of city intersections, according to new data released by the advocacy group Transportation Alternatives.

"If killing a pedestrian with a vehicle were a crime, it would replace attacks with sharp or blunt objects as the second leading homicide in New York City," said Karla Quintero, the group's research coordinator at a rally on the steps of City Hall.

The group identified Canal St. in Manhattan, Flatbush Ave. in Brooklyn, Roosevelt Ave. in Queens, the Grand Concourse in the Bronx and Hylan Blvd. on Staten Island as among the city's worst.

Some 163 pedestrians were killed by cars last year, according to city Department of Transportation data. That's lower than the early 1990s, but is a 4% increase over 2005 - the first increase since 1999. Four people were killed by cars over the weekend.

"Something needs to be done before anther life is taken," said Shaate Draughan, 31, whose 4-year-old son, James Nyprie Rice, was killed in Brooklyn on Feb. 13.

She joined the families of other victims to call for changes in the timing of lights to help people crossing streets; the construction of pedestrian-friendly crosswalks; more stringent investigations, and stricter penalties for drivers who cause deaths.

Earlier, civic leaders and politicians in Queens called on the DOT to add traffic devices along the busy corridor of 73rd Ave. following the vehicular death of a young father last week.

"It's very frustrating," said James Gallagher, president of the Fresh Meadows Homeowners Civic Association. "There's an accident here every other month."

A DOT spokeswoman said that "in the wake of several tragic accidents, it is clear that more needs to be done, and DOT is committed to taking further steps to make the streets as safe as possible."